Caroline A. Lewis

Cell-programmed nutrient partitioning in the tumour microenvironment

Bradley I. Reinfeld, Matthew Z. Madden, Melissa M. Wolf et al. · Nature · 2021 · 942 citations · Full text

Medicine, Biological Microenvironments, Cell Proliferation +6

Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation

Karim Bensaad, Elena Favaro, Caroline A. Lewis et al. · Cell Reports · 2014 · 645 citations · Full text

Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase

Jason R. Cantor, Monther Abu-Remaileh, Naama Kanarek et al. · Cell · 2017 · 629 citations · Full text

Cellular Enzymology, Biochemistry, Natural Sciences +12

Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

Caroline A. Lewis, Seth J. Parker, Brian P. Fiske et al. · Molecular Cell · 2014 · 574 citations · Full text

Energy Metabolism, Biochemistry, Mitochondrial Function +12

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

Michael E. Pacold, Kyle R. Brimacombe, Sze Ham Chan et al. · Nature Chemical Biology · 2016 · 571 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Serine Synthesis +10