Jason R. Cantor

Sestrin2 is a leucine sensor for the mTORC1 pathway

Rachel L. Wolfson, Lynne Chantranupong, Robert A. Saxton et al. · Science · 2015 · 1.2K citations · Full text

Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase

Jason R. Cantor, Monther Abu-Remaileh, Naama Kanarek et al. · Cell · 2017 · 629 citations · Full text

Cellular Enzymology, Biochemistry, Natural Sciences +12

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance

Do‐Hoon Kim, Brian P. Fiske, Kıvanç Birsoy et al. · Nature · 2015 · 358 citations · Full text

Hematological Malignancy, Neuro-oncology, Medicine +10

Histidine catabolism is a major determinant of methotrexate sensitivity

Naama Kanarek, Heather R. Keys, Jason R. Cantor et al. · Nature · 2018 · 308 citations · Full text

Biochemistry, Medicine, Mechanism Of Action +3

Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition

Yoav D. Shaul, Elizaveta Freinkman, William C. Comb et al. · Cell · 2014 · 227 citations · Full text

Chromatin, Skin Development, Natural Sciences +8