Rachel L. Wolfson

Sestrin2 is a leucine sensor for the mTORC1 pathway

Rachel L. Wolfson, Lynne Chantranupong, Robert A. Saxton et al. · Science · 2015 · 1.2K citations · Full text

Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.

Shuyu Wang, Zhi-Yang Tsun, Rachel L. Wolfson et al. · PubMed · 2015 · 801 citations · Full text

mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient

Gregory A. Wyant, Monther Abu-Remaileh, Rachel L. Wolfson et al. · Cell · 2017 · 451 citations · Full text

Mtorc1 Activator Slc38a9, Protein Secretion, Use Protein +6

Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival

Alejo Efeyan, Roberto Zoncu, Steven H. Chang et al. · Nature · 2012 · 443 citations · Full text

Cell Autophagy, Mitophagy, Signal Transduction +10

The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1

Lynne Chantranupong, Rachel L. Wolfson, Jose M. Orozco et al. · Cell Reports · 2014 · 442 citations · Full text