Gregory A. Wyant

Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.

Shuyu Wang, Zhi-Yang Tsun, Rachel L. Wolfson et al. · PubMed · 2015 · 801 citations · Full text

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway

Lynne Chantranupong, Sonia M. Scaria, Robert A. Saxton et al. · Cell · 2016 · 775 citations · Full text

Mtorc1 Pathway, Signal Transduction, Biochemistry +10

Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

Monther Abu-Remaileh, Gregory A. Wyant, Choah Kim et al. · Science · 2017 · 658 citations · Full text

Transformation of the Fallopian Tube Secretory Epithelium Leads to High-Grade Serous Ovarian Cancer in Brca;Tp53;Pten Models

Ruth Perets, Gregory A. Wyant, Katherine W. Muto et al. · Cancer Cell · 2013 · 594 citations · Full text

mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient

Gregory A. Wyant, Monther Abu-Remaileh, Rachel L. Wolfson et al. · Cell · 2017 · 451 citations · Full text

Mtorc1 Activator Slc38a9, Protein Secretion, Use Protein +6