Concepedia

Robert A. Saxton

RA

12

Publications

3.5K

Citations

11

H-Index

2014

Active since

Affiliations

Howard Hughes Medical Institute(Current)

Massachusetts Institute of Technology

Whitehead Institute for Biomedical Research

Broad Institute

Allen Institute

Robert A. Saxton is an author at Howard Hughes Medical Institute specializing in medicine, cell signaling, and signal transduction.

ORCID

Top concepts

Publications per year

2014–2024

12

Publications

12

Sestrin2 is a leucine sensor for the mTORC1 pathway

Rachel L. Wolfson, Lynne Chantranupong, Robert A. Saxton et al. · Science · 2015 · 1.2K citations · Full text

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway

Lynne Chantranupong, Sonia M. Scaria, Robert A. Saxton et al. · Cell · 2016 · 775 citations · Full text

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The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1

Lynne Chantranupong, Rachel L. Wolfson, Jose M. Orozco et al. · Cell Reports · 2014 · 442 citations · Full text

Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway

Robert A. Saxton, Kevin E. Knockenhauer, Rachel L. Wolfson et al. · Science · 2015 · 434 citations · Full text

Mechanism of arginine sensing by CASTOR1 upstream of mTORC1

Robert A. Saxton, Lynne Chantranupong, Kevin E. Knockenhauer et al. · Nature · 2016 · 324 citations · Full text

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