Naama Kanarek

Copper induces cell death by targeting lipoylated TCA cycle proteins

Peter Tsvetkov, Shannon Coy, Boryana Petrova et al. · Science · 2022 · 4.2K citations · Full text

Apoptosis, Cell Death, Cell Death Mechanisms +17

Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase

Jason R. Cantor, Monther Abu-Remaileh, Naama Kanarek et al. · Cell · 2017 · 629 citations · Full text

Cellular Enzymology, Biochemistry, Natural Sciences +12

Histidine catabolism is a major determinant of methotrexate sensitivity

Naama Kanarek, Heather R. Keys, Jason R. Cantor et al. · Nature · 2018 · 308 citations · Full text

Biochemistry, Medicine, Mechanism Of Action +3

Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition

Yoav D. Shaul, Elizaveta Freinkman, William C. Comb et al. · Cell · 2014 · 227 citations · Full text

Chromatin, Skin Development, Natural Sciences +8

mTOR Generates an Auto-Amplification Loop by Triggering the βTrCP- and CK1α-Dependent Degradation of DEPTOR

Shanshan Duan, Jeffrey R. Skaar, Shafi Kuchay et al. · Molecular Cell · 2011 · 192 citations · Full text

Signal Transduction, Biochemistry, Natural Sciences +3