Nanoparticulate Impurities Isolated from Pharmaceutical-Grade Sucrose Are a Potential Threat to Protein Stability

The stabilization of proteins by sucrose.

James Lee, Serge N. Timasheff · Journal of Biological Chemistry · 1981 · 1.1K citations · Full text

Life Sciences, Biochemistry, Biophysics +17

Stabilization of protein structure by sugars

Tsutomu Arakawa, Serge N. Timasheff · Biochemistry · 1982 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +7

Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product Quality

John F. Carpenter, Theodore W. Randolph, Wim Jiskoot et al. · Journal of Pharmaceutical Sciences · 2008 · 588 citations · Full text

Life Sciences, Biochemistry, Pharmaceutics +16

Nucleation: theory and applications to protein solutions and colloidal suspensions

Richard P. Sear · Journal of Physics Condensed Matter · 2007 · 491 citations

Natural Sciences, Biochemistry, Biophysics +17

Protein Instability and Immunogenicity: Roadblocks to Clinical Application of Injectable Protein Delivery Systems for Sustained Release

Wim Jiskoot, Theodore W. Randolph, David B. Volkin et al. · Journal of Pharmaceutical Sciences · 2011 · 250 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +17