Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates

Vasco Filipe, Andrea Hawe, Wim Jiskoot

Pharmaceutical Research

Structural properties of monoclonal antibody aggregates induced by freeze–thawing and thermal stress

Andrea Hawe, Julia Christina Kasper, Wim Jiskoot

European Journal of Pharmaceutical Sciences

Thermal StressStructural PropertiesBiochemistryProtein FoldingNatural Sciences +6

Taylor Dispersion Analysis Compared to Dynamic Light Scattering for the Size Analysis of Therapeutic Peptides and Proteins and Their Aggregates

Andrea Hawe, Wendy L. Hulse, Wim Jiskoot, +1

Pharmaceutical Research

Lyophilized Drug Product Cake Appearance: What Is Acceptable?

Sajal M. Patel, Steven L. Nail, Michael J. Pikal, +5

Journal of Pharmaceutical Sciences

BiomanufacturingExcipientsActive IngredientPharmacologyPharmaceutical Technology +2

Small Amounts of Sub-Visible Aggregates Enhance the Immunogenic Potential of Monoclonal Antibody Therapeutics

Maryam Ahmadi, Christine Bryson, Edward A. Cloake, +7

Pharmaceutical Research

Sub-visible AggregatesAllergyMonoclonal Antibody TherapeuticsImmunoengineeringImmunology +8

Micro–Flow Imaging and Resonant Mass Measurement (Archimedes) – Complementary Methods to Quantitatively Differentiate Protein Particles and Silicone Oil Droplets

Daniel Weinbuch, Sarah Zölls, Michael Wiggenhorn, +3

Journal of Pharmaceutical Sciences

EngineeringBiomedical DiagnosticsMicroscopyMass SpectrometryMicrorheology +9

Flow Imaging Microscopy for Protein Particle Analysis—A Comparative Evaluation of Four Different Analytical Instruments

Sarah Zölls, Daniel Weinbuch, Michael Wiggenhorn, +3

The AAPS Journal

EngineeringMicroscope Image ProcessingMicroscopyMedicineMicroscopy Method +9

How Subvisible Particles Become Invisible—Relevance of the Refractive Index for Protein Particle Analysis

Sarah Zölls, Manuel Gregoritza, Ruedeeporn Tantipolphan, +3

Journal of Pharmaceutical Sciences

Optical Particle SizingMicroscopyNatural SciencesMolecular BiologyBiomedical Analysis +6

Quality of Original and Biosimilar Epoetin Products

Vera Brinks, Andrea Hawe, Abdul Basmeleh, +5

Pharmaceutical Research

Ongoing Challenges to Develop High Concentration Monoclonal Antibody-based Formulations for Subcutaneous Administration: Quo Vadis?

Wim Jiskoot, Andrea Hawe, Tim Menzen, +2

Journal of Pharmaceutical Sciences