Christine Bryson

Comprehensive Rare Variant Analysis via Whole-Genome Sequencing to Determine the Molecular Pathology of Inherited Retinal Disease

Keren Carss, Gavin Arno, Marie Erwood et al. · The American Journal of Human Genetics · 2016 · 463 citations · Full text

Whole-genome Sequencing, Allelic Variant, Genetic Disorder +11

Immunogenicity of protein therapeutics: The key causes, consequences and challenges

Matthew Baker, Helen Reynolds, Brooke Lumicisi et al. · Self/Nonself · 2010 · 349 citations · Full text

Immunodeficiencies, Immunology, Immunodominance +16

Small Amounts of Sub-Visible Aggregates Enhance the Immunogenic Potential of Monoclonal Antibody Therapeutics

Maryam Ahmadi, Christine Bryson, Edward A. Cloake et al. · Pharmaceutical Research · 2014 · 162 citations

Sub-visible Aggregates, Allergy, Monoclonal Antibody Therapeutics +10

Use of In Vitro Assays to Assess Immunogenicity Risk of Antibody-Based Biotherapeutics

Marisa K. Joubert, Meghana Deshpande, Jane Yang et al. · PLoS ONE · 2016 · 112 citations · Full text

Clinical Immunology, Immunohematology, Vitro Assays +27

Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes

James Whitworth, Philip Smith, Jose‐Ezequiel Martín et al. · The American Journal of Human Genetics · 2018 · 70 citations · Full text

Tumor Biology, Somatic Variant, Broad Range +13