Protein Instability and Immunogenicity: Roadblocks to Clinical Application of Injectable Protein Delivery Systems for Sustained Release

Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates

Vasco Filipe, Andrea Hawe, Wim Jiskoot · Pharmaceutical Research · 2010 · 1.8K citations · Full text

Pharmacy, Biophysics, Pharmaceutics +17

Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product Quality

John F. Carpenter, Theodore W. Randolph, Wim Jiskoot et al. · Journal of Pharmaceutical Sciences · 2008 · 588 citations · Full text

Life Sciences, Biochemistry, Pharmaceutics +16

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

Fiona A. Sharp, Darren Ruane, Benjamin Claass et al. · Proceedings of the National Academy of Sciences · 2009 · 536 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Polymeric protein delivery systems

Kuen Yong Lee, Soon Hong Yuk · Progress in Polymer Science · 2007 · 418 citations

Pharmacy, Pharmaceutics, Drug Delivery +11

Strategies for the Assessment of Protein Aggregates in Pharmaceutical Biotech Product Development

John den Engelsman, Patrick Garidel, Ronald Smulders et al. · Pharmaceutical Research · 2010 · 350 citations · Full text

Life Sciences, Biotechnology, Pharmaceutical Biotechnology +17