C. Russell Middaugh

Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product Quality

John F. Carpenter, Theodore W. Randolph, Wim Jiskoot et al. · Journal of Pharmaceutical Sciences · 2008 · 578 citations · Full text

Protein Chemistry, Biochemistry, Subvisible Particles +10

Statistical determination of the average values of the extinction coefficients of tryptophan and tyrosine in native proteins

Henryk Mach, C. Russell Middaugh, Randolph V. Lewis · Analytical Biochemistry · 1992 · 450 citations

Biology, Protein Chemistry, Biochemistry +6

Silicone Oil Induced Aggregation of Proteins

LaToya S. Jones, Allyn M. Kaufmann, C. Russell Middaugh · Journal of Pharmaceutical Sciences · 2005 · 276 citations

Microemulsion, Protein Engineering, Protein Phase Separation +2

Biophysical Characterization of PEI/DNA Complexes

Sirirat Choosakoonkriang, Brian A. Lobo, Gary S. Koe et al. · Journal of Pharmaceutical Sciences · 2003 · 265 citations

Natural Sciences, Pei/dna Complexes, Molecular Biology +7

Protein Instability and Immunogenicity: Roadblocks to Clinical Application of Injectable Protein Delivery Systems for Sustained Release

Wim Jiskoot, Theodore W. Randolph, David B. Volkin et al. · Journal of Pharmaceutical Sciences · 2011 · 248 citations

Vaccination, Sustained Release, Protein Instability +10