Biophysical Characterization of PEI/DNA Complexes

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

A Novel Non-Viral Vector for DNA Delivery Based on Low Molecular Weight, Branched Polyethylenimine: Effect of Molecular Weight on Transfection Efficiency and Cytotoxicity

Dagmar Fischer, Thorsten Bieber, Youxin Li et al. · Pharmaceutical Research · 1999 · 1.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle

W.T. Godbey, Kenneth K. Wu, Antonios G. Mikos · Journal of Biomedical Materials Research · 1999 · 822 citations

Pharmacy, Bioengineering, Biotechnology +16

The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes

MX Tang, FC Szoka · Gene Therapy · 1997 · 804 citations

Natural Sciences, Biochemistry, Chemistry +15

A Powerful Nonviral Vector for <i>In Vivo</i> Gene Transfer into the Adult Mammalian Brain: Polyethylenimine

Bassima Abdallah, Corinne Benoist, Daniel Goula et al. · Human Gene Therapy · 1996 · 542 citations

Life Sciences, Molecular Biology, Neuroscience +16