Concepedia

Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro

Susanne Neumann, Elena Eliseeva, Alisa Boutin, Elena Barnaeva, Marc Ferrer, Noel Southall, David Kim, Xin Hu, Sarah J. Morgan, Juan Marugán,

Journal of Pharmacology and Experimental Therapeutics · 2017 · 23 citations · 23 references

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23

Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries

James Inglese, Douglas S. Auld, Ajit Jadhav et al. · Proceedings of the National Academy of Sciences · 2006 · 820 citations · Full text

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TSH Is a Negative Regulator of Skeletal Remodeling

Etsuko Abe, Russell Marians, Wanqin Yu et al. · Cell · 2003 · 693 citations · Full text

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The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families.

Karl‐Ludwig Laugwitz, Anouk Allgeier, Stefan Offermanns et al. · Proceedings of the National Academy of Sciences · 1996 · 318 citations

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Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65

Xi‐Ping Huang, Joel Karpiak, Wesley K. Kroeze et al. · Nature · 2015 · 287 citations

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A Family of Highly Selective Allosteric Modulators of the Metabotropic Glutamate Receptor Subtype 5

Julie A. O’Brien, Wei Lemaire, Tsing‐Bau Chen et al. · Molecular Pharmacology · 2003 · 209 citations

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