Douglas S. Auld

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

Dimitrios Anastasiou, George Poulogiannis, John M. Asara et al. · Science · 2011 · 1.2K citations · Full text

Lipid Peroxidation, Cell Death, Metabolic Remodeling +19

Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries

James Inglese, Douglas S. Auld, Ajit Jadhav et al. · Proceedings of the National Academy of Sciences · 2006 · 806 citations · Full text

Drug Target, Hit Identification, Concentration-response Curves +23

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Dimitrios Anastasiou, Yimin Yu, William J. Israelsen et al. · Nature Chemical Biology · 2012 · 804 citations · Full text

COPI Complex Is a Regulator of Lipid Homeostasis

Mathias Beller, Carole Sztalryd, Noel Southall et al. · PLoS Biology · 2008 · 328 citations · Full text

Metabolic Syndrome, Signal Transduction, Copi Complex +15

Assay Guidance Manual [Internet]

Sarine Markossian, A Grossman, Kyle R. Brimacombe et al. · 2004 · 287 citations

Pharmaceutical Research, Drug Target, Biochemistry +15