BindProfX: Assessing Mutation-Induced Binding Affinity Change by Protein Interface Profiles with Pseudo-Counts

Amino acid substitution matrices from protein blocks.

Steven Henikoff, Jorja G. Henikoff · Proceedings of the National Academy of Sciences · 1992 · 6.3K citations · Full text

Genetics, Molecular Biology, Genomics +19

Lethality and centrality in protein networks

Hawoong Jeong, S. P. Mason, Albert-Ĺaszló Barabási et al. · Nature · 2001 · 5.3K citations · Full text

Biology, Network Science, Engineering +8

TM-align: a protein structure alignment algorithm based on the TM-score

Yang Zhang · Nucleic Acids Research · 2005 · 3.8K citations · Full text

The FoldX web server: an online force field

Joost Schymkowitz, Jean‐Paul Borg, François Stricher et al. · Nucleic Acids Research · 2005 · 2.8K citations · Full text

Free Energy, Engineering, Protein Assembly +18

Profile analysis: detection of distantly related proteins.

Michael Gribskov, A. McLachlan, David Eisenberg · Proceedings of the National Academy of Sciences · 1987 · 1.3K citations · Full text

Engineering, Genetics, Protein Analysis +21