Concepedia

Binding Affinity Profiling

Binding Affinity Profiling is a computational or experimental methodology within selectivity profiling that quantifies the strength and specificity of molecular interactions between a target biomolecule and a set of ligands to determine their relative binding affinities.

171

Publications

9.3K

Citations

1.1K

Authors

405

Institutions

Publications per year

2017–2026

62

Parents

Publications

171

Modified deoxyoligonucleotides stable to exonuclease degradation in serum

Jeng‐Pyng Shaw, Kenneth M. Kent, Jeff Bird et al. · Nucleic Acids Research · 1991 · 369 citations · Full text

, , +16

Quantitative Structure-Activity Relationship of Various Endogenous Estrogen Metabolites for Human Estrogen Receptor α and β Subtypes: Insights into the Structural Determinants Favoring a Differential Subtype Binding

Bao Ting Zhu, Gui‐Zhen Han, Joong‐Youn Shim et al. · Endocrinology · 2006 · 270 citations

, , +17

Fluorine-NMR Experiments for High-Throughput Screening:  Theoretical Aspects, Practical Considerations, and Range of Applicability

Claudio Dalvit, Paul E. Fagerness, Daneen T. A. Hadden et al. · Journal of the American Chemical Society · 2003 · 247 citations

, , +16

De novo identification and biophysical characterization of transcription-factor binding sites with microfluidic affinity analysis

Polly M. Fordyce, Doron Gerber, Danh Tran et al. · Nature Biotechnology · 2010 · 192 citations

, , +16

Origins of netropsin binding affinity and specificity: correlations of thermodynamic and structural data.

Luis A. Marky, Kenneth J. Breslauer · Proceedings of the National Academy of Sciences · 1987 · 188 citations · Full text

, , +17

1–5 of 171

Authors

1.1K

  1. HF
    Hank F. Kung

    University of Pennsylvania, United States

    3 publications · 45 citations

    3

    h-index

  2. DS
    David S. Hage

    University of Nebraska–Lincoln, United States

    3 publications · 158 citations

    3

    h-index

  3. JK
    Jeroen Kool

    Vrije Universiteit Amsterdam, Netherlands

    3 publications · 88 citations

    3

    h-index

  4. HI
    Hubertus Irth

    Vrije Universiteit Amsterdam, Netherlands

    2 publications · 58 citations

    2

    h-index

  5. FS
    Ferrán Sanz

    Universitat Pompeu Fabra, Spain

    2 publications · 48 citations

    2

    h-index

1–5 of 1.1K

Institutions

405

  1. National Institute on Drug Abuse

    Bethesda, United States

    4 h-index

    17 publications

    492 citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    24 publications

    1K citations

  3. Uppsala University

    Uppsala, Sweden

    4 h-index

    7 publications

    211 citations

  4. National Institutes of Health

    Bethesda, United States

    4 h-index

    11 publications

    692 citations

  5. University of Nebraska–Lincoln

    Lincoln, United States

    3 h-index

    9 publications

    564 citations

  6. National Cancer Institute

    Bethesda, United States

    3 h-index

    13 publications

    208 citations

  7. Technical University of Munich

    Munich, Germany

    3 h-index

    13 publications

    392 citations

  8. University of Oxford

    Oxford, United Kingdom

    3 h-index

    5 publications

    254 citations

1–8 of 405

Venues

  1. Journal of Medicinal Chemistry

    18 publications · 975 citations

    16

    h-index

  2. Analytical Chemistry

    4 publications · 85 citations

    4

    h-index

  3. Analytical Biochemistry

    4 publications · 130 citations

    4

    h-index

  4. PLoS ONE

    4 publications · 195 citations

    4

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 570 citations

    4

    h-index

1–5