Protein Interface Evolution

Protein Interface Evolution is the evolutionary process by which the physical and chemical characteristics of the contact regions between interacting proteins change over time, driven by selective pressures to maintain, modify, or diversify interaction specificity and affinity.

148

Publications

12.8K

Citations

546

Authors

221

Institutions

Publications per year

2017–2026

Parents

Protein-protein Interactions

Children

Adaptive Evolution Of Binding InterfacesAllosteric Effects On InterfacesBinding Affinity EvolutionCo-evolutionary AnalysisConvergent Evolution Of InterfacesEpistasis In Protein InterfacesEvolutionary Rate AnalysisInterface PlasticityInterface RemodelingInterface Residue Conservation

Publications

148

An Evolutionary Trace Method Defines Binding Surfaces Common to Protein Families

Olivier Lichtarge, Henry R. Bourne, Fred E. Cohen · Journal of Molecular Biology · 1996 · 1.2K citations

Life Sciences, Biochemistry, Bioinformatics +12

Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary information

Sergey Ovchinnikov, Hetunandan Kamisetty, David Baker · eLife · 2014 · 710 citations · Full text

Life Sciences, Biochemistry, Bioinformatics +17

Relating Three-Dimensional Structures to Protein Networks Provides Evolutionary Insights

Philip M. Kim, Long Lu, Yu Xia et al. · Science · 2006 · 476 citations

Life Sciences, Biochemistry, Evolutionary Biology +15

Structure, function, and evolution of transient and obligate protein–protein interactions

Julian Mintseris, Zhiping Weng · Proceedings of the National Academy of Sciences · 2005 · 377 citations · Full text

Life Sciences, Biology, Evolutionary Biology +17

[18] Systematic mutational analyses of protein-protein interfaces

James A. Wells · Methods in enzymology on CD-ROM/Methods in enzymology · 1991 · 345 citations

Life Sciences, Biochemistry, Molecular Biology +12

1–5 of 148

Authors

546

RG
Raphaël Guérois
Commissariat à l'Énergie Atomique et aux Énergies Alternatives, France
7 publications · 318 citations
7
h-index
JA
Jessica Andréani
Centre National de la Recherche Scientifique, France
6 publications · 269 citations
6
h-index
OL
Olivier Lichtarge
Baylor College of Medicine, United States
4 publications · 1.4K citations
4
h-index
RN
Ruth Nussinov
Tel Aviv University, Israel
4 publications · 778 citations
4
h-index
AC
Alessandra Carbone
Sorbonne Université, France
4 publications · 176 citations
4
h-index

1–5 of 546

Institutions

221

1–8 of 221

Venues

Proceedings of the National Academy of Sciences
PNAS · 24 publications · 2.5K citations
23
h-index
Proteins Structure Function and Bioinformatics
12 publications · 855 citations
12
h-index
Journal of Molecular Biology
JMB · 11 publications · 2.1K citations
11
h-index
PLoS Computational Biology
9 publications · 398 citations
9
h-index
Protein Science
PS · 7 publications · 366 citations
7
h-index

1–5