Concepedia

Interface Residue Conservation

Interface Residue Conservation is a metric that quantifies the degree to which amino acid residues at protein-protein interaction interfaces remain unchanged across homologous protein sequences during evolution, distinguishing it from general sequence conservation by specifically focusing on functionally critical interfacial positions.

60

Publications

5.6K

Citations

218

Authors

112

Institutions

Publications per year

2017–2026

6

Parents

Publications

60

Predicting functionally important residues from sequence conservation

John A. Capra, Mona Singh · Bioinformatics · 2007 · 741 citations

, , +12

Residue frequencies and pairing preferences at protein-protein interfaces

Fabian Glaser, David M. Steinberg, Ilya A. Vakser et al. · Proteins Structure Function and Bioinformatics · 2001 · 381 citations

, , +15

Are protein–protein interfaces more conserved in sequence than the rest of the protein surface?

Daniel R. Caffrey, Shyamal Somaroo, Jason D. Hughes et al. · Protein Science · 2003 · 344 citations · Full text

, , +14

Protein-protein interfaces: Analysis of amino acid conservation in homodimers

William Valdar, Janet M. Thornton · Proteins Structure Function and Bioinformatics · 2000 · 328 citations

, , +15

Conservation of polar residues as hot spots at protein interfaces

Zengjian Hu, Buyong Ma, Haim J. Wolfson et al. · Proteins Structure Function and Bioinformatics · 2000 · 284 citations

, , +15

1–5 of 60

Authors

218

  1. PC
    Pinak Chakrabarti

    Bose Institute, India

    4 publications · 666 citations

    4

    h-index

  2. JJ
    Joël Janin

    Centre National de la Recherche Scientifique, France

    3 publications · 310 citations

    3

    h-index

  3. MG
    Mainak Guharoy

    Vrije Universiteit Brussel, Belgium

    3 publications · 384 citations

    3

    h-index

  4. RN
    Ruth Nussinov

    Tel Aviv University, Israel

    3 publications · 378 citations

    3

    h-index

  5. HJ
    Haim J. Wolfson

    Tel Aviv University, Israel

    2 publications · 303 citations

    2

    h-index

1–5 of 218

Institutions

112

  1. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    19 publications

    1K citations

  2. Tel Aviv University

    Tel Aviv, Israel

    5 h-index

    11 publications

    1.9K citations

  3. Bose Institute

    Kolkata, India

    4 h-index

    9 publications

    1.4K citations

  4. Science Applications International Corporation (United States)

    McLean, United States

    3 h-index

    3 publications

    378 citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    7 publications

    900 citations

  6. Indian Institute of Science Bangalore

    Bengaluru, India

    3 h-index

    14 publications

    665 citations

  7. Wake Forest University

    Winston-Salem, United States

    2 h-index

    7 publications

    1.3K citations

  8. Birkbeck, University of London

    London, United Kingdom

    2 h-index

    2 publications

    345 citations

1–8 of 112

Venues

  1. Proteins Structure Function and Bioinformatics

    17 publications · 1.8K citations

    14

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 913 citations

    6

    h-index

  3. Protein Science

    PS · 5 publications · 503 citations

    5

    h-index

  4. Journal of Molecular Biology

    JMB · 4 publications · 379 citations

    4

    h-index

  5. Biochemistry

    4 publications · 232 citations

    4

    h-index

1–5