Daniel R. Caffrey

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis et al. · Nature · 2009 · 2.5K citations · Full text

Signal Transduction, Natural Sciences, Cell Interaction +12

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF

Katherine A. Fitzgerald, Daniel C. Rowe, Betsy Barnes et al. · The Journal of Experimental Medicine · 2003 · 1.2K citations · Full text

A Long Noncoding RNA Mediates Both Activation and Repression of Immune Response Genes

Susan Carpenter, Daniel Aiello, Maninjay Atianand et al. · Science · 2013 · 942 citations · Full text

Structure-based maximal affinity model predicts small-molecule druggability

Alan C. Cheng, Ryan G. Coleman, Kathleen T Smyth et al. · Nature Biotechnology · 2007 · 684 citations

Drug Target, Medicine, Small-molecule Druggability +6

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

Monika Gulia-Nuss, Andrew B. Nuss, Jason M. Meyer et al. · Nature Communications · 2016 · 539 citations · Full text