Andrea Ablasser

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis et al. · Nature · 2009 · 2.5K citations · Full text

Signal Transduction, Natural Sciences, Cell Interaction +12

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Andrea Ablasser, Marion Goldeck, Taner Cavlar et al. · Nature · 2013 · 1.6K citations · Full text

Nucleic Acid Chemistry, Signal Transduction, Molecular Physiology +6

Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7

Veit Hornung, Margit Guenthner‐Biller, Carole Bourquin et al. · Nature Medicine · 2005 · 1.2K citations · Full text

Innate Immune System, Immunology, Immune Regulation +16

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence

Selene Glück, Baptiste Guey, Muhammet F. Gülen et al. · Nature Cell Biology · 2017 · 1.1K citations · Full text

Chromatin, Innate Immune Sensing, Cytosolic Chromatin Fragments +10

Targeting STING with covalent small-molecule inhibitors

Simone M. Haag, Muhammet F. Gülen, Luc Reymond et al. · Nature · 2018 · 1K citations · Full text

Medicinal Chemistry, Drug Target, Drug Targeting +7