Concepedia

Interface Remodeling

Interface Remodeling is a computational or analytical framework in structural biology that specifically characterizes the structural and energetic alterations at protein-protein interaction interfaces during evolution, distinguishing it from broader models of protein evolution by focusing exclusively on interfacial reorganization as a functional adaptation mechanism.

18

Publications

1.5K

Citations

57

Authors

38

Institutions

Publications per year

2017–2026

5

Parents

Publications

18

Energetics of protein-protein interactions: Analysis ofthe Barnase-Barstar interface by single mutations and double mutant cycles

Gideon Schreiber, Alan R. Fersht · Journal of Molecular Biology · 1995 · 573 citations

, , +15

A Simple Definition of Structural Regions in Proteins and Its Use in Analyzing Interface Evolution

Emmanuel D. Levy · Journal of Molecular Biology · 2010 · 269 citations

, , +16

Structural Plasticity in a Remodeled Protein-Protein Interface

S. Atwell, Mark Ultsch, Abraham M. de Vos et al. · Science · 1997 · 183 citations

, , +17

Structural response to mutation at a protein-protein interface 1 1Edited by R. Huber

Cara K. Vaughan, Ashley M. Buckle, Alan R. Fersht · Journal of Molecular Biology · 1999 · 73 citations

, , +13

Structural Basis of a Rationally Rewired Protein-Protein Interface Critical to Bacterial Signaling

Anna Podgornaia, Patricia Casino, Alberto Marina et al. · Structure · 2013 · 71 citations · Full text

, , +15

1–5 of 18

Authors

57

  1. AR
    Alan R. Fersht

    Medical Research Council, United Kingdom

    2 publications · 646 citations

    2

    h-index

  2. CX
    Changhu Xue

    Ocean University of China, China

    1 publications · 54 citations

    1

    h-index

  3. JL
    Junmeng Lu

    Zhejiang Gongshang University, China

    1 publications · 42 citations

    1

    h-index

  4. MH
    Michael Hsing

    University of British Columbia, Canada

    1 publications · 30 citations

    1

    h-index

  5. JA
    James A. Wells

    University of California, San Francisco, United States

    1 publications · 183 citations

    1

    h-index

1–5 of 57

Institutions

38

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    1 publications

    71 citations

  2. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    2 h-index

    2 publications

    842 citations

  3. Instituto de Salud Carlos III

    Madrid, Spain

    1 h-index

    1 publications

    71 citations

  4. Ministry of Education of the People's Republic of China

    Beijing, China

    1 h-index

    4 publications

    168 citations

  5. Institut de Biologia Molecular de Barcelona

    Barcelona, Spain

    1 h-index

    1 publications

    71 citations

  6. National Institutes of Health

    Bethesda, United States

    1 h-index

    2 publications

    28 citations

  7. Ocean University of China

    Qingdao, China

    1 h-index

    7 publications

    378 citations

  8. Medical Research Council

    London, United Kingdom

    1 h-index

    1 publications

    573 citations

1–8 of 38

Venues

  1. Journal of Molecular Biology

    JMB · 3 publications · 915 citations

    3

    h-index

  2. Food Hydrocolloids

    2 publications · 96 citations

    2

    h-index

  3. Structure

    1 publications · 71 citations

    2

    h-index

  4. Journal of the American Chemical Society

    JACS · 2 publications · 72 citations

    2

    h-index

  5. Journal of Computational Biology

    1 publications · 30 citations

    1

    h-index

1–5