Alan R. Fersht

Hydrogen bonding and biological specificity analysed by protein engineering

Alan R. Fersht, Jianping Shi, J.W. Knill-Jones et al. · Nature · 1985 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +16

The Structure of the Transition State for Folding of Chymotrypsin Inhibitor 2 Analysed by Protein Engineering Methods: Evidence for a Nucleation-condensation Mechanism for Protein Folding

Laura S. Itzhaki, Daniel E. Otzen, Alan R. Fersht · Journal of Molecular Biology · 1995 · 747 citations

Life Sciences, Biochemistry, Biophysics +16

Mapping the transition state and pathway of protein folding by protein engineering

Andreas Matouschek, James T. Kellis, Luis Serrano et al. · Nature · 1989 · 707 citations

Life Sciences, Biochemistry, Molecular Biology +16

Energetics of protein-protein interactions: Analysis ofthe Barnase-Barstar interface by single mutations and double mutant cycles

Gideon Schreiber, Alan R. Fersht · Journal of Molecular Biology · 1995 · 573 citations

Life Sciences, Biochemistry, Molecular Biology +15

The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

Paul J. Carter, Greg Winter, Anthony J. Wilkinson et al. · Cell · 1984 · 567 citations

Life Sciences, Biochemistry, Molecular Biology +11