Concepedia

CRISPR/Cas9-Mediated Correction of the Sickle Mutation in Human CD34+ cells

Megan D. Hoban, Dianne Lumaquin, Caroline Y. Kuo, Zulema Romero, Joseph Long, Michelle Ho, Courtney S. Young, Michelle Mojadidi, Sorel Fitz‐Gibbon, Aaron Cooper,

Molecular Therapy · 2016 · 216 citations · 30 references

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References

30

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

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Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

F. Ann Ran, Patrick D. Hsu, Chie-Yu Lin et al. · Cell · 2013 · 3.4K citations · Full text

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

Yanfang Fu, Jennifer A Foden, Cyd Khayter et al. · Nature Biotechnology · 2013 · 3.3K citations · Full text

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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

Shengdar Q. Tsai, Zongli Zheng, Nathalie T. Nguyen et al. · Nature Biotechnology · 2014 · 2.3K citations · Full text

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

Yanfang Fu, Jeffry D. Sander, Deepak Reyon et al. · Nature Biotechnology · 2014 · 2K citations · Full text

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