Molecular Pharmacology · 1998 · 37 citations · 31 references
Life SciencesBiochemistryPharmacologyDrug DiscoveryEnzymologyMolecular PharmacologyEnzyme InhibitionEnzyme KineticsFarnesyl Diphosphate SynthaseInhibitor ScreeningOncogenic TransformationSqualene Synthase
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All ras proteins are polyisoprenylated but only some are palmitoylated
John F. Hancock, Anthony I. Magee, Julie E. Childs et al. · Cell · 1989 · 1.8K citations
Inhibition of purified p21 farnesyl:protein transferase by Cys-AAX tetrapeptides
Yuval Reiss, Joseph L. Goldstein, Miguel C. Seabra et al. · Cell · 1990 · 815 citations