Concepedia

Oncogenic Transformation

Oncogenic Transformation is a biological process in which normal cells acquire cancerous properties through genetic or epigenetic alterations that confer uncontrolled proliferation, evasion of growth suppression, and potential for tumor formation, distinguishing it from non-transformed cellular states.

8.1K

Publications

584.7K

Citations

49.1K

Authors

5K

Institutions

Publications per year

2017–2026

2.8K

Variants

Cellular Transformation

Parents

Publications

8.1K

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

Hartmut Land, Luis F. Parada, Robert A. Weinberg · Nature · 1983 · 2.9K citations

, , +16

TEAD mediates YAP-dependent gene induction and growth control

Bin Zhao, Xin Ye, Jindan Yu et al. · Genes & Development · 2008 · 2.5K citations · Full text

, , +16

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

Mara Roxana Rubinstein, Xiaowei Wang, Wendy Liu et al. · Cell Host & Microbe · 2013 · 2.4K citations · Full text

, , +17

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

Tathiane M. Malta, Artem Sokolov, Andrew J. Gentles et al. · Cell · 2018 · 2.3K citations · Full text

, , +17

A Landscape of Pharmacogenomic Interactions in Cancer

Francesco Iorio, Theo Knijnenburg, Daniël J. Vis et al. · Cell · 2016 · 2.3K citations · Full text

, , +17

1–5 of 8.1K

Authors

49.1K

  1. PK
    Peter K. Vogt

    Scripps Research Institute, United States

    41 publications · 5.4K citations

    29

    h-index

  2. EJ
    Eric J. Hall

    Columbia University, United States

    34 publications · 1.8K citations

    24

    h-index

  3. SA
    Stuart A. Aaronson

    National Cancer Institute, United States

    21 publications · 5.4K citations

    19

    h-index

  4. RA
    Robert A. Weinberg

    Whitehead Institute for Biomedical Research, United States

    21 publications · 7.8K citations

    19

    h-index

  5. RC
    Richard C. Miller

    Columbia University, United States

    23 publications · 976 citations

    18

    h-index

1–5 of 49.1K

Institutions

5K

  1. Harvard University

    Cambridge, United States

    97 h-index

    905 publications

    164.3K citations

  2. Dana-Farber Cancer Institute

    Boston, United States

    82 h-index

    832 publications

    154.3K citations

  3. National Cancer Institute

    Bethesda, United States

    80 h-index

    875 publications

    152.2K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    75 h-index

    391 publications

    82.3K citations

  5. Sun Yat-sen University

    Guangzhou, China

    63 h-index

    1.2K publications

    81.3K citations

  6. The University of Texas MD Anderson Cancer Center

    Houston, United States

    63 h-index

    745 publications

    76K citations

  7. National Institutes of Health

    Bethesda, United States

    62 h-index

    486 publications

    74.4K citations

  8. University of California, San Francisco

    San Francisco, United States

    61 h-index

    444 publications

    39.5K citations

1–8 of 5K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 404 publications · 64.5K citations

    142

    h-index

  2. Cancer Research

    309 publications · 30.5K citations

    101

    h-index

  3. PubMed

    Repository · 675 publications · 37.6K citations

    98

    h-index

  4. Molecular and Cellular Biology

    MCB · 304 publications · 29.6K citations

    97

    h-index

  5. Journal of Biological Chemistry

    JBC · 202 publications · 17.8K citations

    75

    h-index

1–5