Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression

Antibodies, a laboratory manual

Biomedicine & Pharmacotherapy · 1989 · 12.5K citations

Pharmacy, Biochemistry, Molecular Biology +9

A new technique for the assay of infectivity of human adenovirus 5 DNA

Frank L. Graham, A.J. van der Eb · Virology · 1973 · 9.7K citations

Life Sciences, Infectious Diseases, Molecular Biology +10

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

Life Sciences, Cancer Biology, Molecular Biology +10

Regulation of p53 stability by Mdm2

Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden · Nature · 1997 · 3.3K citations

Life Sciences, Cancer Biology, Molecular Biology +10

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

Medicine, Molecular Biology, Oncology +10