Gerard P. Zambetti

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

Oncogenic Agent, Medicine, Molecular Biology +9

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

Takehiko Kamijo, Jason D. Weber, Gerard P. Zambetti et al. · Proceedings of the National Academy of Sciences · 1998 · 897 citations · Full text

Gain of function mutations in p53

Dirk P. Dittmer, Sibani Pati, Gerard P. Zambetti et al. · Nature Genetics · 1993 · 895 citations

Genome Instability, Molecular Biology, Function Mutations +4

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

John Jeffers, Evan Parganas, Youngsoo Lee et al. · Cancer Cell · 2003 · 868 citations · Full text

Tumor Biology, -Independent Apoptotic Pathways, Medicine +9

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

Hyungjin Kim, Mubina Rafiuddin-Shah, Ho-Chou Tu et al. · Nature Cell Biology · 2006 · 857 citations

Mitochondrial Function, Hierarchical Regulation, Apoptosis +7