Concepedia

Gain of function mutations in p53

Dirk P. Dittmer, Sibani Pati, Gerard P. Zambetti, Shelley Chu, Angelika K. Teresky, Mary Moore, Cathy A. Finlay, Arnold J. Levine

Nature Genetics · 1993 · 900 citations · 38 references

DOI

Concepts

References

38

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

Martin Scheffner, Bruce A. Werness, Jon M. Huibregtse et al. · Cell · 1990 · 4K citations

, , +14

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

, , +10

Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53

Bruce A. Werness, Arnold J. Levine, Peter M. Howley · Science · 1990 · 2.6K citations

, , +17

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

Suzanne J. Baker, Eric R. Fearon, Janice Nigro et al. · Science · 1989 · 2.1K citations

, , +16

The p53 proto-oncogene can act as a suppressor of transformation

Cathy A. Finlay, Philip W. Hinds, Arnold J. Levine · Cell · 1989 · 2K citations

, , +12