Martin Scheffner

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

Martin Scheffner, Bruce A. Werness, Jon M. Huibregtse et al. · Cell · 1990 · 4K citations

Human Papillomavirus Vaccines, Medicine, Pathology +10

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

Martin Scheffner, Jon M. Huibregtse, Richard D. Vierstra et al. · Cell · 1993 · 2.4K citations

Hpv-16 E6, Ubiquitin-protein Ligase, Protein Function +4

Protein ubiquitination involving an E1–E2–E3 enzyme ubiquitin thioester cascade

Martin Scheffner, Ulrike A. Nuber, Jon M. Huibregtse · Nature · 1995 · 1K citations

Protein Chemistry, Protein Function, Biochemistry +5

A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18.

Jon M. Huibregtse, Martin Scheffner, Peter M. Howley · The EMBO Journal · 1991 · 879 citations · Full text

Medicine, Pathology, E6 Oncoprotein +10

The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines.

Martin Scheffner, Karl Münger, J C Byrne et al. · Proceedings of the National Academy of Sciences · 1991 · 866 citations · Full text

Tumor Biology, Cervical Cancer, Oncogenic Agent +15