Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors

Evan Parganas, Demin Wang, Dimitrios J. Stravopodis, +9

Cell

InflammationCytokineSignal TransductionSignaling PathwayReceptor Tyrosine Kinase +8

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

John Jeffers, Evan Parganas, Youngsoo Lee, +10

Cancer Cell

Tumor Biology-Independent Apoptotic PathwaysMedicineApoptosisAutophagy +7

SOCS1 Deficiency Causes a Lymphocyte-Dependent Perinatal Lethality

Jean‐Christophe Marine, David J. Topham, Catriona McKay, +5

Cell

Autoimmune DiseaseImmune Cell DevelopmentImmunologySocs1 DeficiencyAutoimmunity +2

Phospholipase Cγ2 Is Essential in the Functions of B Cell and Several Fc Receptors

Demin Wang, Jian Feng, Renren Wen, +8

Immunity

InflammationSignal TransductionSignaling PathwaySeveral Fc ReceptorsImmunology +9

SOCS3 regulates the plasticity of gp130 signaling

Roland Lang, Anne‐Laure Pauleau, Evan Parganas, +5

Nature Immunology

Signal TransductionSignaling PathwayMolecular RegulationGene ExpressionMedicine +3

SOCS3 Is Essential in the Regulation of Fetal Liver Erythropoiesis

Jean‐Christophe Marine, Catriona McKay, Demin Wang, +8

Cell

Signal TransductionDevelopmental BiologySignaling PathwayLiver PhysiologyHeme Signaling +6

Stat5 Is Essential for the Myelo- and Lymphoproliferative Disease Induced by TEL/JAK2

Juerg Schwaller, Evan Parganas, Demin Wang, +12

Molecular Cell

Hematological MalignancyImmunologyHematologyPathologyAutoimmunity +7

Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26.

Kazuhiro Morishita, Evan Parganas, Carroll L. William, +6

Proceedings of the National Academy of Sciences

Hematological MalignancyChromatinTranscriptional RegulationEvi1 Gene ExpressionMedicine +12

The genomic landscape of core-binding factor acute myeloid leukemias

Zachary Faber, Xiang Chen, Amanda Larson Gedman, +46

Nature Genetics

Hematological MalignancyChromatinFunctional GenomicsGenomic LandscapeMixed-phenotype Acute Leukemia +4

Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations.

Giuseppina Nucifora, Catherine R. Begy, Hirofumi Kobayashi, +6

Proceedings of the National Academy of Sciences

EngineeringMixed-phenotype Acute LeukemiaGeneticsMolecular BiologyBand Q26 +21