Biochemical Pharmacology · 2016 · 54 citations · 22 references
Life SciencesBiotechnologyMolecular BiologyGenome EditingGenome EngineeringCrispr-based EngineeringCrispr-cas SystemsCytochrome P450 EnzymesCytochrome P450-mediated MetabolismKnockout Animal ModelsCrispr-cas9 Genome EditingCrispr-cas9 KnockoutCrispr-cas9 Knockout ModelsCrispr-cas9 ValidationKnockout Rat Models
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The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
Josiane E. Garneau, Marie-Ève Dupuis, Manuela Villion et al. · Nature · 2010 · 2.3K citations
David R. Nelson · Human Genomics · 2009 · 1K citations · Full text
Role of CYP2E1 in the Hepatotoxicity of Acetaminophen
Susanna S.T. Lee, Jeroen Buters, Thierry Pineau et al. · Journal of Biological Chemistry · 1996 · 658 citations · Full text
Medicine, Pharmacology, Toxicology +15
CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos
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