Yuting Guan

CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos

Yanjiao Shao, Yuting Guan, Liren Wang et al. · Nature Protocols · 2014 · 196 citations

Developmental Biology, Cell Modification, Engineering +11

<scp>CRISPR</scp> /Cas9‐mediated somatic correction of a novel coagulator factor <scp>IX</scp> gene mutation ameliorates hemophilia in mouse

Yuting Guan, Yanlin Ma, Qi Li et al. · EMBO Molecular Medicine · 2016 · 166 citations · Full text

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

Xin Sheng, Yuting Guan, Ziyuan Ma et al. · Nature Genetics · 2021 · 154 citations · Full text

Allelic Variant, Kidney Transplant, Medicine +11

Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Liang Chen, Biyun Zhu, Gaomeng Ru et al. · Nature Biotechnology · 2022 · 148 citations

Engineering, Genome Surgery, Genetic Engineering +10

Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos

Liang Chen, Mengjia Hong, Changming Luan et al. · Nature Biotechnology · 2023 · 106 citations

Developmental Biology, Medicine, Natural Sciences +8