Yuting Guan

CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos

Yanjiao Shao, Yuting Guan, Liren Wang et al. · Nature Protocols · 2014 · 203 citations

Life Sciences, Genetics, Molecular Genetics +15

CRISPR/Cas9‐mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse

Yuting Guan, Yanlin Ma, Qi Li et al. · EMBO Molecular Medicine · 2016 · 170 citations · Full text

Life Sciences, Biotechnology, Genetics +15

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

Xin Sheng, Yuting Guan, Ziyuan Ma et al. · Nature Genetics · 2021 · 164 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Liang Chen, Biyun Zhu, Gaomeng Ru et al. · Nature Biotechnology · 2022 · 156 citations

Life Sciences, Genetics, Molecular Biology +14

Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos

Liang Chen, Mengjia Hong, Changming Luan et al. · Nature Biotechnology · 2023 · 117 citations

Life Sciences, Genetics, Molecular Biology +15