Xin Sheng

Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis

Ki Wung Chung, Poonam Dhillon, Shizheng Huang et al. · Cell Metabolism · 2019 · 636 citations · Full text

Medicine, Cell Biology, Nephrology +16

Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis

Verónica Miguel, Jessica Tituaña, J. Ignacio Herrero et al. · Journal of Clinical Investigation · 2021 · 332 citations · Full text

Veterinary Medicine, Biochemistry, Pathobiology +17

Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease

Hongbo Liu, Tomohito Doke, Dong Guo et al. · Nature Genetics · 2022 · 214 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation

Poonam Dhillon, Jihwan Park, Carmen Hurtado del Pozo et al. · Cell Metabolism · 2020 · 175 citations · Full text

Life Sciences, Molecular Biology, Nephrology +14

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

Xin Sheng, Yuting Guan, Ziyuan Ma et al. · Nature Genetics · 2021 · 164 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16