Tomohito Doke

Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease

Hongbo Liu, Tomohito Doke, Dong Guo et al. · Nature Genetics · 2022 · 203 citations · Full text

Renal Function, Functional Genomics, Transcriptomic Analyses +15

Single-cell analysis highlights differences in druggable pathways underlying adaptive or fibrotic kidney regeneration

Michael S. Balzer, Tomohito Doke, Ya‐Wen Yang et al. · Nature Communications · 2022 · 172 citations · Full text

The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation

Poonam Dhillon, Jihwan Park, Carmen Hurtado del Pozo et al. · Cell Metabolism · 2020 · 165 citations · Full text

Urology, Molecular Physiology, Signal Transduction +12

Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis

Tomohito Doke, Amin Abedini, Daniel L. Aldridge et al. · Nature Immunology · 2022 · 126 citations · Full text

Inflammation, Fibrosis, Urology +14

NAD+ flux is maintained in aged mice despite lower tissue concentrations

Melanie R. McReynolds, Karthikeyani Chellappa, Eric Chiles et al. · Cell Systems · 2021 · 106 citations · Full text

Aging, Biochemistry, Longevity +12