Liren Wang

Dual base editor catalyzes both cytosine and adenine base conversions in human cells

Xiaohui Zhang, Biyun Zhu, Liang Chen et al. · Nature Biotechnology · 2020 · 287 citations

Cellular Enzymology, Biochemistry, Adenine Base Conversions +11

CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos

Yanjiao Shao, Yuting Guan, Liren Wang et al. · Nature Protocols · 2014 · 196 citations

Developmental Biology, Cell Modification, Engineering +11

Engineering a precise adenine base editor with minimal bystander editing

Liang Chen, Shun Zhang, Niannian Xue et al. · Nature Chemical Biology · 2022 · 168 citations

Engineering, Computational Biology, Molecular Biology +3

<scp>CRISPR</scp> /Cas9‐mediated somatic correction of a novel coagulator factor <scp>IX</scp> gene mutation ameliorates hemophilia in mouse

Yuting Guan, Yanlin Ma, Qi Li et al. · EMBO Molecular Medicine · 2016 · 166 citations · Full text

CRISPR–Cas9-mediated gene editing of the BCL11A enhancer for pediatric β0/β0 transfusion-dependent β-thalassemia

Bin Fu, Jiaoyang Liao, Shuanghong Chen et al. · Nature Medicine · 2022 · 163 citations

Gene Therapies, Genetics, Hematology +9