Dual base editor catalyzes both cytosine and adenine base conversions in human cells

Xiaohui Zhang, Biyun Zhu, Liang Chen, +23

Nature Biotechnology

Cellular EnzymologyBiochemistryAdenine Base ConversionsHuman CellsNatural Sciences +9

CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos

Yanjiao Shao, Yuting Guan, Liren Wang, +8

Nature Protocols

Developmental BiologyCell ModificationEngineeringGenetic EngineeringOne-cell Embryos +9

Engineering a precise adenine base editor with minimal bystander editing

Liang Chen, Shun Zhang, Niannian Xue, +21

Nature Chemical Biology

EngineeringComputational BiologyMolecular BiologyGenome EditingBiomolecular Engineering +1

<scp>CRISPR</scp> /Cas9‐mediated somatic correction of a novel coagulator factor <scp>IX</scp> gene mutation ameliorates hemophilia in mouse

Yuting Guan, Yanlin Ma, Qi Li, +15

EMBO Molecular Medicine

CRISPR–Cas9-mediated gene editing of the BCL11A enhancer for pediatric β0/β0 transfusion-dependent β-thalassemia

Bin Fu, Jiaoyang Liao, Shuanghong Chen, +13

Nature Medicine

Gene TherapiesGeneticsHematologyGenetic EngineeringGene Editing +7

Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Liang Chen, Biyun Zhu, Gaomeng Ru, +22

Nature Biotechnology

EngineeringGenome SurgeryGenetic EngineeringSynthetic BiologyDna Replication +8

A Design of Greenhouse Monitoring &amp;#x00026; Control System Based on ZigBee Wireless Sensor Network

Yiming Zhou, Xianglong Yang, Xishan Guo, +2

Sensor NetworksSmart SensorEnergy HarvestingEnvironmental MonitoringEngineering +13

Increasing the efficiency and targeting range of cytidine base editors through fusion of a single-stranded DNA-binding protein domain

Xiaohui Zhang, Liang Chen, Biyun Zhu, +17

Nature Cell Biology

BiochemistryNatural SciencesOligonucleotideMolecular BiologyDna Replication +6

Structure and function of Norrin in assembly and activation of a Frizzled 4–Lrp5/6 complex

Jiyuan Ke, Kaleeckal G. Harikumar, Clara Erice, +10

Genes & Development

A wireless solution for greenhouse monitoring and control system based on ZigBee technology

Qian Zhang, Xianglong Yang, Yiming Zhou, +2

Journal of Zhejiang University. Science A