Shun Zhang

Acute‐on‐chronic liver failure precipitated by hepatic injury is distinct from that precipitated by extrahepatic insults

Yu Shi, Ying Yang, Yaoren Hu et al. · Hepatology · 2015 · 311 citations

Proteomic and metabolomic profiling of urine uncovers immune responses in patients with COVID-19

Xiaojie Bi, Wei Liu, Xuan Ding et al. · Cell Reports · 2021 · 175 citations · Full text

Engineering a precise adenine base editor with minimal bystander editing

Liang Chen, Shun Zhang, Niannian Xue et al. · Nature Chemical Biology · 2022 · 168 citations

Engineering, Computational Biology, Molecular Biology +3

Self-amplifying loop of NF-κB and periostin initiated by PIEZO1 accelerates mechano-induced senescence of nucleus pulposus cells and intervertebral disc degeneration

Jinna Wu, Yuyu Chen, Zhiheng Liao et al. · Molecular Therapy · 2022 · 150 citations · Full text

Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Liang Chen, Biyun Zhu, Gaomeng Ru et al. · Nature Biotechnology · 2022 · 148 citations

Engineering, Genome Surgery, Genetic Engineering +10