Biyun Zhu

Dual base editor catalyzes both cytosine and adenine base conversions in human cells

Xiaohui Zhang, Biyun Zhu, Liang Chen et al. · Nature Biotechnology · 2020 · 287 citations

Cellular Enzymology, Biochemistry, Adenine Base Conversions +11

AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial

Jun Lv, Hui Wang, Xiaoting Cheng et al. · The Lancet · 2024 · 277 citations

Gene Therapies, Aav1-hotof Gene Therapy, Single-arm Trial +6

Engineering a precise adenine base editor with minimal bystander editing

Liang Chen, Shun Zhang, Niannian Xue et al. · Nature Chemical Biology · 2022 · 168 citations

Engineering, Computational Biology, Molecular Biology +3

Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Liang Chen, Biyun Zhu, Gaomeng Ru et al. · Nature Biotechnology · 2022 · 148 citations

Engineering, Genome Surgery, Genetic Engineering +10

Increasing the efficiency and targeting range of cytidine base editors through fusion of a single-stranded DNA-binding protein domain

Xiaohui Zhang, Liang Chen, Biyun Zhu et al. · Nature Cell Biology · 2020 · 135 citations

Biochemistry, Natural Sciences, Oligonucleotide +8