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5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part 1: Structure–activity relationship studies of 5-alkylamino pyrazoles and discovery of a potent, selective, and orally active analog

5-Alkylamino PyrazolesMolecular PharmacologyMedicinal ChemistryBiochemistryCanine Cox-2 InhibitorsMedicineNatural SciencesPharmacological AgentActive AnalogPharmacotherapyDrug DevelopmentPharmacologyPharmaceutical ChemistryDrug Discovery