Martha L. Minich

Discovery of (<i>S</i>)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1<i>H</i>-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus

Jeffrey A. Pfefferkorn, Angel Guzmán-Pérez, John Litchfield et al. · Journal of Medicinal Chemistry · 2011 · 115 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Pyridones as glucokinase activators: Identification of a unique metabolic liability of the 4-sulfonyl-2-pyridone heterocycle

Jeffrey A. Pfefferkorn, Jihong Lou, Martha L. Minich et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 80 citations · Full text

Life Sciences, Biochemistry, Pharmacology +10

Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2

Jeffrey W. Corbett, Kevin D. Freeman‐Cook, Richard L. Elliott et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 58 citations · Full text

Life Sciences, Biochemistry, Pharmacology +12

5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part 1: Structure–activity relationship studies of 5-alkylamino pyrazoles and discovery of a potent, selective, and orally active analog

Subas M. Sakya, Kristin M. Lundy DeMello, Martha L. Minich et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 51 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Synthesis of compounds designed to inhibit bacterial cell wall transglycosylation

Scott J. Hecker, Martha L. Minich, Karen Lackey · The Journal of Organic Chemistry · 1990 · 44 citations

Pharmacy, Biochemistry, Medicinal Chemistry +10