Concepedia

Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2

Jeffrey W. Corbett, Kevin D. Freeman‐Cook, Richard L. Elliott, F.F. Vajdos, Francis Rajamohan, Darcy Kohls, Eric S. Marr, Hailong Zhang, Liang Tong, Meihua Tu,

Bioorganic & Medicinal Chemistry Letters · 2009 · 58 citations · 5 references

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Isozyme-nonselective N-Substituted Bipiperidylcarboxamide Acetyl-CoA Carboxylase Inhibitors Reduce Tissue Malonyl-CoA Concentrations, Inhibit Fatty Acid Synthesis, and Increase Fatty Acid Oxidation in Cultured Cells and in Experimental Animals

H. James Harwood, Stephen F. Petras, Lorraine D. Shelly et al. · Journal of Biological Chemistry · 2003 · 243 citations · Full text

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Human acetyl-CoA carboxylase: characterization, molecular cloning, and evidence for two isoforms.

Lutfi Abu-Elheiga, Arumugam Jayakumar, Antonio Baldini et al. · Proceedings of the National Academy of Sciences · 1995 · 188 citations

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Acetyl Coenzyme A Carboxylase System of Escherichia coli

S.E. Polakis, Ras B. Guchhait, Eberhard E. Zwergel et al. · Journal of Biological Chemistry · 1974 · 100 citations · Full text

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Activation of acetyl-CoA carboxylase. Purification and properties of a Mn2+-dependent phosphatase.

K G Thampy, Salih J. Wakil · Journal of Biological Chemistry · 1985 · 84 citations · Full text

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Crystal Structure of the Carboxyltransferase Domain of Acetyl-Coenzyme A Carboxylase in Complex with CP-640186

Hailong Zhang, Benjamin Tweel, Jiang Li et al. · Structure · 2004 · 81 citations · Full text

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