H. James Harwood

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

Robert Svensson, Seth J. Parker, Lillian J. Eichner et al. · Nature Medicine · 2016 · 501 citations · Full text

Tumor Biology, Oncology, Oncogenic Agent +12

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma

James Lally, Sarani Ghoshal, Danielle K. DePeralta et al. · Cell Metabolism · 2018 · 395 citations · Full text

Oxysterol, Biochemistry, Medicine +8

The characterization of sequence distribution in copolymers

H. James Harwood, W. M. Ritchey · Journal of Polymer Science Part B Polymer Letters · 1964 · 319 citations

Materials Science, Block Co-polymers, Engineering +7

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats

Geraldine Harriman, Jeremy R. Greenwood, Sathesh Bhat et al. · Proceedings of the National Academy of Sciences · 2016 · 275 citations · Full text

Fatty Liver Disease, Insulin Signaling, Metabolic Syndrome +18

Isozyme-nonselective N-Substituted Bipiperidylcarboxamide Acetyl-CoA Carboxylase Inhibitors Reduce Tissue Malonyl-CoA Concentrations, Inhibit Fatty Acid Synthesis, and Increase Fatty Acid Oxidation in Cultured Cells and in Experimental Animals

H. James Harwood, Stephen F. Petras, Lorraine D. Shelly et al. · Journal of Biological Chemistry · 2003 · 243 citations · Full text