Seth J. Parker

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

Cosimo Commisso, Shawn M. Davidson, Rengin G. Soydaner-Azeloglu et al. · Nature · 2013 · 1.6K citations

Protein Function, Signal Transduction, Ras-transformed Cells +11

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

Keisuke Yamamoto, Anthony Venida, Julian Yano et al. · Nature · 2020 · 1.1K citations · Full text

Cell Autophagy, Immune Evasion, Pancreatic Cancer +7

Reductive carboxylation supports redox homeostasis during anchorage-independent growth

Lei Jiang, Alexander A. Shestov, Pamela Swain et al. · Nature · 2016 · 582 citations · Full text

Redox Regulator, Anchorage-independent Growth, Cell Growth +4

Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

Caroline A. Lewis, Seth J. Parker, Brian P. Fiske et al. · Molecular Cell · 2014 · 574 citations · Full text

Energy Metabolism, Biochemistry, Mitochondrial Function +12

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

Robert Svensson, Seth J. Parker, Lillian J. Eichner et al. · Nature Medicine · 2016 · 501 citations · Full text

Tumor Biology, Oncology, Oncogenic Agent +12