Geraldine Harriman

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

Robert Svensson, Seth J. Parker, Lillian J. Eichner et al. · Nature Medicine · 2016 · 520 citations

Medicine, Biochemistry, Oncology +17

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma

James Lally, Sarani Ghoshal, Danielle K. DePeralta et al. · Cell Metabolism · 2018 · 409 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats

Geraldine Harriman, Jeremy R. Greenwood, Sathesh Bhat et al. · Proceedings of the National Academy of Sciences · 2016 · 284 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Acetyl‐coenzyme A carboxylase inhibition reduces de novo lipogenesis in overweight male subjects: A randomized, double‐blind, crossover study

Kathryn Stiede, Wenyan Miao, Heather Blanchette et al. · Hepatology · 2017 · 115 citations · Full text

Medicine, Biochemistry, Pharmacology +17

A Selective Small Molecule IκB Kinase β Inhibitor Blocks Nuclear Factor κB-Mediated Inflammatory Responses in Human Fibroblast-Like Synoviocytes, Chondrocytes, and Mast Cells

Danyi Wen, Yuhua Nong, Jennifer G. Morgan et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 113 citations

Medicine, Medicinal Chemistry, Pharmacology +17