Sathesh Bhat

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

Robert Svensson, Seth J. Parker, Lillian J. Eichner et al. · Nature Medicine · 2016 · 501 citations · Full text

Tumor Biology, Oncology, Oncogenic Agent +12

Solvated Interaction Energy (SIE) for Scoring Protein−Ligand Binding Affinities. 1. Exploring the Parameter Space

Marwen Naïm, Sathesh Bhat, Kathryn N. Rankin et al. · Journal of Chemical Information and Modeling · 2007 · 419 citations

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma

James Lally, Sarani Ghoshal, Danielle K. DePeralta et al. · Cell Metabolism · 2018 · 395 citations · Full text

Oxysterol, Biochemistry, Medicine +8

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats

Geraldine Harriman, Jeremy R. Greenwood, Sathesh Bhat et al. · Proceedings of the National Academy of Sciences · 2016 · 275 citations · Full text

Fatty Liver Disease, Insulin Signaling, Metabolic Syndrome +18

Docking performance of the glide program as evaluated on the Astex and DUD datasets: a complete set of glide SP results and selected results for a new scoring function integrating WaterMap and glide

Matthew P. Repasky, Robert B. Murphy, Jay L. Banks et al. · Journal of Computer-Aided Molecular Design · 2012 · 154 citations

Engineering, Data Science, Aerospace Engineering +5