Subas M. Sakya

Mannopeptimycins, Novel Antibacterial Glycopeptides from <i>Streptomyces </i><i>h</i><i>ygroscopicus</i>, LL-AC98

Haiyin He, R. Thomas Williamson, Bo Shen et al. · Journal of the American Chemical Society · 2002 · 149 citations

Glycobiology, Novel Antibiotics, Antimicrobial Chemotherapy +16

Inverse electron demand Diels-Alder reactions of 3,6-bis(methylthio)-1,2,4,5-tetrazine. 1,2-Diazine introduction and direct implementation of a divergent 1,2,4,5-tetrazine .fwdarw. 1,2-diazine .fwdarw. benzene (indoline/indole) Diels-Alder strategy

Dale L. Boger, Subas M. Sakya · The Journal of Organic Chemistry · 1988 · 111 citations

1,2-Diazine .Fwdarw, Divergent 1,2,4,5-Tetrazine .Fwdarw, Heterocyclic +9

Discovery, SAR, and Pharmacokinetics of a Novel 3-Hydroxyquinolin-2(1<i>H</i>)-one Series of Potent<scp>d</scp>-Amino Acid Oxidase (DAAO) Inhibitors

Allen J. Duplantier, Stacey L. Becker, Michael J. Bohanon et al. · Journal of Medicinal Chemistry · 2009 · 109 citations · Full text

Synthesis and evaluation of aborted and extended CC-1065 functional analogs: (+)- and (-)-CPI-PDE-I1, (+)- and (-)-CPI-CDPI1, and (.+-.)-, (+)-, and (-)-CPI-CDPI3. Preparation of key partial structures and definition of an additional functional role of the CC-1065 central and right-hand subunits

Dale L. Boger, Robert S. Coleman, Benedict J. Invergo et al. · Journal of the American Chemical Society · 1990 · 78 citations

Combinatorial Chemistry, Medicinal Chemistry, Engineering +15

Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors

Michael A. Brodney, Elizabeth M. Beck, Christopher R. Butler et al. · Journal of Medicinal Chemistry · 2015 · 78 citations · Full text

Reduce Risk, Drug Target, Peptide Science +21