John Litchfield

Identification of Glyoxal and Arabinose as Intermediates in the Autoxidative Modification of Proteins by Glucose

Kevin J. Wells‐Knecht, David V. Zyzak, John Litchfield et al. · Biochemistry · 1995 · 588 citations

Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions

Manthena V. S. Varma, Yurong Lai, Bo Feng et al. · Pharmaceutical Research · 2012 · 128 citations

Pharmacokinetic Modeling, Hepatology, Medicine +8

Quantitative Prediction of Human Renal Clearance and Drug-Drug Interactions of Organic Anion Transporter Substrates Using In Vitro Transport Data: A Relative Activity Factor Approach

Sumathy Mathialagan, Mary Piotrowski, David A. Tess et al. · Drug Metabolism and Disposition · 2017 · 127 citations

pH-Sensitive Interaction of HMG-CoA Reductase Inhibitors (Statins) with Organic Anion Transporting Polypeptide 2B1

Manthena V. S. Varma, Charles J. Rotter, Kevin M. Whalen et al. · Molecular Pharmaceutics · 2011 · 117 citations

Discovery of (<i>S</i>)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1<i>H</i>-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus

Jeffrey A. Pfefferkorn, Angel Guzmán-Pérez, John Litchfield et al. · Journal of Medicinal Chemistry · 2011 · 114 citations · Full text