Angewandte Chemie International Edition · 2010 · 48 citations · 20 references
Protein AssemblyProteasomeMolecular BiologyChemical BiologyStructure-function Enzyme KineticsProteomicsProtein ChemistryProteasome Active SubunitsBiochemistryBiomolecular AnalysisCleavable LinkerActivity‐based ProteinProtein BioinformaticsBiomolecular EngineeringNatural SciencesLevulinoyl EsterProtein EngineeringCell ExtractsTitle Linker
Get linked: The title linker is stable under various biological conditions and can be cleaved chemoselectively with hydrazine (see scheme). Its use is demonstrated in the activity-based enrichment and identification of proteasome active subunits from cell extracts.
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Cell Surface Engineering by a Modified Staudinger Reaction
Eliana Saxon, Carolyn R. Bertozzi · Science · 2000 · 2.4K citations