Activity-Based Protein Profiling is a chemoproteomic method that uses active-site-directed, covalent small-molecule probes to selectively tag, enrich, and analyze catalytically active proteins within complex biological systems, thereby enabling proteome-wide assessment of enzyme function.
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563
Orlistat Is a Novel Inhibitor of Fatty Acid Synthase with Antitumor Activity
Steven J. Kridel, Fumiko Axelrod, Natasha Rozenkrantz et al. · Cancer Research · 2004 · 601 citations · Full text
Medicine, Oncology, Pharmacology +16
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Scripps Research Institute
San Diego, United States
45 h-index
328 publications
36.3K citations
Leiden University
Leiden, The Netherlands
27 h-index
260 publications
12.6K citations
National University of Singapore
Singapore, Singapore
24 h-index
119 publications
8.5K citations
Harvard University
Cambridge, United States
22 h-index
131 publications
10.4K citations
University of California, Berkeley
Berkeley, United States
18 h-index
96 publications
12K citations
Technical University of Munich
Munich, Germany
16 h-index
73 publications
3.6K citations
University of Oxford
Oxford, United Kingdom
15 h-index
72 publications
7.2K citations
Stanford University
Stanford, United States
14 h-index
43 publications
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32 publications · 1.8K citations
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20 publications · 1.1K citations
19
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PNAS · 19 publications · 4K citations
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MCP · 22 publications · 1.4K citations
17
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