Concepedia

Enzyme Selectivity Mapping

Enzyme Selectivity Mapping is a methodological framework in chemical biology that systematically identifies and characterizes the substrate or inhibitor specificity profiles of enzymes across complex biological systems using activity-based probes.

9

Publications

398

Citations

38

Authors

18

Institutions

Publications per year

2017–2026

1

Parents

Publications

9

Structural Biasing Elements for In-Cell Histone Deacetylase Paralog Selectivity

Jason Chun Yu Wong, Roger Hong, Stuart L. Schreiber · Journal of the American Chemical Society · 2003 · 112 citations

, , +12

Mapping the Active Site of Angiotensin-Converting Enzyme by Transferred NOE Spectroscopy

Moriz Mayer, Bernd Meyer · Journal of Medicinal Chemistry · 2000 · 68 citations

, , +16

Merging the Binding Sites of Aldose and Aldehyde Reductase for Detection of Inhibitor Selectivity-determining Features

H. Steuber, A. Heine, A. Podjarny et al. · Journal of Molecular Biology · 2008 · 56 citations

, , +16

Classifying Enzymes from Selectivity Fingerprints

Johann Grognux, Jean‐Louis Reymond · ChemBioChem · 2004 · 52 citations

, , +17

Identification of a Selectivity Determinant for Inhibition of Tumor Necrosis Factor-α Converting Enzyme by Comparative Modeling

Zelda R. Wasserman, James J.‐W. Duan, Matthew E. Voss et al. · Chemistry & Biology · 2003 · 42 citations · Full text

, , +16

1–5 of 9

Authors

38

  1. CX
    Chu‐Biao Xue

    Incyte (United States), United States

    1 publications · 42 citations

    1

    h-index

  2. YU
    Yuki Usami

    Kyushu Institute of Technology, Japan

    1 publications · 26 citations

    1

    h-index

  3. MO
    Motonori Ohno

    Kyushu University, Japan

    1 publications · 11 citations

    1

    h-index

  4. RJ
    Robert J. Cherney

    Bristol-Myers Squibb (United States), United States

    1 publications · 42 citations

    1

    h-index

  5. JI
    Jin‐ichi Inokuchi

    Tohoku Medical and Pharmaceutical University, Japan

    1 publications · 26 citations

    1

    h-index

1–5 of 38

Institutions

18

  1. Sylvester Comprehensive Cancer Center

    Miami, United States

    1 h-index

    2 publications

    42 citations

  2. Inserm

    Paris, France

    1 h-index

    1 publications

    56 citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    1 h-index

    3 publications

    336 citations

  4. Japan Agency for Marine-Earth Science and Technology

    Yokosuka, Japan

    1 h-index

    1 publications

    26 citations

  5. Experimental Station

    Chicago, United States

    1 h-index

    8 publications

    336 citations

  6. Bristol-Myers Squibb (United States)

    New York, United States

    1 h-index

    8 publications

    336 citations

  7. Kyushu University

    Fukuoka, Japan

    1 h-index

    2 publications

    22 citations

  8. Philipps University of Marburg

    Marburg, Germany

    1 h-index

    3 publications

    168 citations

1–8 of 18

Venues

  1. 1

    h-index

  2. Nature Communications

    1 publications · 21 citations

    1

    h-index

  3. Journal of Chemical Education

    1 publications · 10 citations

    1

    h-index

  4. Journal of Medicinal Chemistry

    1 publications · 68 citations

    1

    h-index

  5. Journal of Molecular Biology

    JMB · 1 publications · 56 citations

    1

    h-index

1–5