Concepedia

Cleavable Linkers

Cleavable Linkers is a chemical construct in polymer and material science that functions as a molecular bridge designed to undergo selective and controlled bond scission under specific environmental or biochemical stimuli, thereby enabling the targeted degradation of macromolecular systems.

260

Publications

15K

Citations

1.6K

Authors

485

Institutions

Publications per year

2017–2026

120

Parents

Publications

260

Design and development of polymeric micelles with cleavable links for intracellular drug delivery

Hua Wei, Ren‐Xi Zhuo, Xian‐Zheng Zhang · Progress in Polymer Science · 2012 · 471 citations

, , +16

Organic Semiconducting Pro‐nanostimulants for Near‐Infrared Photoactivatable Cancer Immunotherapy

Dong Cui, Jiaguo Huang, Shasha He et al. · Angewandte Chemie International Edition · 2019 · 306 citations

, , +17

Methyl 4-mercaptobutyrimidate as a cleavable crosslinking reagent and its application to the Escherichia coli 30S ribosome

Robert R. Traut, Alex Bollen, Tung‐Tien Sun et al. · Biochemistry · 1973 · 290 citations

, , +9

Efficacy and Safety of Patritumab Deruxtecan (HER3-DXd) in EGFR Inhibitor–Resistant, <i>EGFR</i> -Mutated Non–Small Cell Lung Cancer

Cancer Discovery · 2021 · 287 citations · Full text

, , +17

Aptamer‐PROTAC Conjugates (APCs) for Tumor‐Specific Targeting in Breast Cancer

Shipeng He, Fei Gao, Junhui Ma et al. · Angewandte Chemie International Edition · 2021 · 285 citations

, , +15

1–5 of 260

Authors

1.6K

  1. KP
    Kanyi Pu

    Nanyang Technological University, Singapore

    9 publications · 1.3K citations

    9

    h-index

  2. SH
    Shasha He

    Nanyang Technological University, Singapore

    6 publications · 711 citations

    6

    h-index

  3. DC
    Dong Cui

    Nanyang Technological University, Singapore

    5 publications · 995 citations

    5

    h-index

  4. HW
    Herbert Waldmann

    Max Planck Institute of Molecular Physiology, Germany

    5 publications · 124 citations

    5

    h-index

  5. JH
    Jiaguo Huang

    Nanyang Technological University, Singapore

    4 publications · 716 citations

    4

    h-index

1–5 of 1.6K

Institutions

485

  1. Nanyang Technological University

    Singapore, Singapore

    9 h-index

    41 publications

    6.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    21 publications

    1.5K citations

  3. Chinese Academy of Sciences

    Beijing, China

    6 h-index

    28 publications

    1.7K citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    6 h-index

    6 publications

    444 citations

  5. Dana-Farber Cancer Institute

    Boston, United States

    5 h-index

    20 publications

    2.2K citations

  6. Max Planck Institute of Molecular Physiology

    Dortmund, Germany

    5 h-index

    13 publications

    322 citations

  7. University of California, Davis

    Davis, United States

    5 h-index

    21 publications

    670 citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    5 h-index

    21 publications

    1.3K citations

1–8 of 485

Venues

  1. Angewandte Chemie International Edition

    18 publications · 1.7K citations

    17

    h-index

  2. Bioconjugate Chemistry

    25 publications · 726 citations

    16

    h-index

  3. Chemical Communications

    ChemComm · 9 publications · 397 citations

    9

    h-index

  4. Angewandte Chemie

    8 publications · 324 citations

    8

    h-index

  5. Journal of the American Chemical Society

    JACS · 6 publications · 362 citations

    6

    h-index

1–5